Met Éíreann has issued a Status Orange snow and ice warning for the east and southeast of the country for this Sunday.
The Orange alert is for counties Dublin, Kildare, Louth, Wexford, Wicklow, Meath and Waterford.
Scattered heavy snow showers are expected along with some "associated drifting", according to Met Éireann.
The warning comes into effect at 3am on Sunday morning and will remain in place until noon that day.
The snow warning comes just two weeks after many parts of Ireland were hit with heavy snowfalls that lead to widespread disruption.
Separately, a Status Yellow snow and ice warning is in place for the rest of the country this weekend.
There will be snow showers also but some areas staying dry, especially the northwest.
This warning is in place from noon tomorrow until 9am on Monday morning.
Met Éireann said it will be very cold this weekend with wind chill and icy patches.
Gardaí have advised people to be conscious of local conditions and take appropriate precautions.
As St Patrick's Day parades get under way across the country tomorrow, showers will progressively turn more wintry.
Most of the showers will be in the east, but a few will reach the midlands and south as well.
There will be some accumulations of snow on high ground at first, but on lower levels later as well.
Temperatures will range from 1-3C in the eastern half of the country while it will be slightly warmer in the west with highs of 4-6C.
Blustery easterly winds will also add a significant wind chill, according to Met Éireann.