Former DUP leader Edwin Poots has failed in a bid to switch constituencies in the forthcoming Northern Ireland Assembly elections.
Mr Poots, a current Lagan Valley MLA, had tried to secure a seat in the South Down constituency.
The Stormont Minister for Agriculture was interviewed by DUP officers as part of the selection process this evening, along with another candidate, Diane Forsythe.
But tonight the party picked Ms Forsythe over Mr Poots at a selection meeting.
She and her father, DUP councillor Glyn Hanna, had temporarily left the party over the ousting of former leader Arlene Foster by Mr Poots and his allies.
They later rejoined the DUP when Jeffrey Donaldson replaced Mr Poots as leader after just three weeks.
Mr Poots currently represents the neighbouring Lagan Valley constituency alongside his DUP colleague and Stormont First Minister, Paul Givan.
But with party leader Jeffrey Donaldson - Lagan Valley's current Westminster MP - also announcing his intention to run for an assembly seat in that constituency, the prospect of winning three seats seemed remote.
Mr Poots could now contest the Westminster seat relinquished by Mr Donaldson.
But he has made no public comment on his intentions.
He was filmed leaving the selection meeting and when asked by reporters how it had gone, Mr Poots said it "went very well".
The fall-out from the selection process could also mark the end of the political career of another long-standing DUP figure.
Former DUP MLA Jim Wells had represented the South Down constituency for many years.
But in recent years he had some differences with his party and lost the whip - though he maintained close links with his party colleagues.
He was effectively deselected by his constituency association as part of the selection process.
It is not clear whether he might opt to run as an independent.
In a statement, the DUP paid tribute to Mr Wells for "his long and distinguished service to both the party and the wider cause of Unionism over the last 40 years".