A jury has been sworn in for the trial of seven people accused of a range of charges including the repeated rape, sexual assault, abuse and sexual exploitation of three children.

The jury was told the seven on trial include the children's parents and members of their extended family. The parents also face charges of neglect in relation to a total of five children.

It took more than an hour for 91 charges to be read out at the Central Criminal Court this afternoon.

It is alleged that some of the children were repeatedly raped and sexually assaulted and were assaulted by being medicated and that they were made to engage in sexual activity with other children and adults.

Each of the seven defendants has pleaded not guilty to the offences which are alleged to have happened between 2014 and 2016.

Mr Justice Paul McDermott told the jury the children are now aged 14, 12 and 11 and neither they nor the accused can be identified at any stage.

He told the jury the trial is expected to last eight to ten weeks and for that reason he was empaneling an enlarged jury of 15 people.

The children's father has pleaded not guilty to 34 charges including rape, sexual assault, sexual exploitation, assault and neglect of his children.

His wife has pleaded not guilty to 25 charges including sexual assault, sexual exploitation and assault, including allowing the children to be sexually assaulted by others. She also faces charges of neglect.

Another man, aged 48, has denied 12 charges including rape, sexual assault and sexual exploitation of three of the children.

A 35-year-old woman has pleaded not guilty to three charges of sexual assault of two of the children.

A 27-year-old man has pleaded not guilty to ten charges including rape, sexual assault and sexual exploitation.

A 32-year-old woman has pleaded not guilty to four charges including sexual assault and sexual exploitation of two of the children.

A 57-year-old woman has pleaded not guilty to three charges of sexual assault.

The prosecution is expected to open the case before the jury on Monday.