The Department of Health has confirmed 1,144 new cases of Covid-19.
There are 384 people in hospital with Covid-19, up 22 on yesterday. The number of people being treated in ICU remains at 59.
In Northern Ireland, nine deaths related to Covid-19 have been reported in the last 24 hours, while 1,764 new cases were confirmed.
The latest data from the Health Protection Surveillance Centre shows a further reduction in the 14-day incidence of Covid-19 in Ireland.
Data compiled up to 1 September puts the 14-day incidence at 491 cases for every 100,000 people.
Under its most recent optimistic projections, NPHET suggested that daily cases numbers could reach 3,000 a day, by the middle of this month.
The latest HPSC report puts the average daily case numbers for the two weeks to 1 September at 1,670.
NPHET also projected up to 700 hospitalisations and 130 patients in ICU by the middle of the month.
Meanwhile, the European Medicines Agency has started evaluating an application for the use of a booster dose of the Pfizer vaccine.
The booster shot would be given six months after the second dose to people over the age of 16.
It said it would carry out an accelerated assessment of data submitted by Pfizer, including results from an ongoing clinical trial, in which around 300 adults with healthy immune systems received a booster dose around six months after the second dose.
The EMA said that the outcome of the evaluation is expected in the next few weeks.
Separately, the EMA said it is evaluating data from the literature on the use of an extra dose of the Pfizer vaccine in severely immunocompromised people.
So far, around 89.3% of adults in Ireland are fully vaccinated.
Of those aged 16 years and older, 87.9% are fully jabbed, while 82.6% of those aged over 12 are fully vaccinated.
The percentage of the total population fully vaccinated is 69.1%.
Health Service Executive CEO Paul Reid said that 9,500 people were given vaccines at walk-in vaccination centres over the weekend.
In a post on Twitter, he said that over 50% of those who attended were in the 12 to 15 age group.
More than 6.9 million vaccines have been administered so far and around 89% of the adult population has been fully vaccinated against Covid-19, with around 92% partially vaccinated.
Good to see that another 9,500 people availed of the Walk In Vaccination Centres over the weekend. Positively, over 50% of these were in the 12 to 15 age groups. The walk in centres have proven to provide a very flexible option for all age groups. @HSELive— Paul Reid (@paulreiddublin) September 6, 2021
Minister for Health Stephen Donnelly said the seventh millionth vaccine dose will be administered this week and the impact of Ireland's vaccination programme continues to be seen across the population.
He tweeted that the "downward trend in Covid-19 infections is now also very evident in younger age groups".
The impact of vaccinations continues to be seen across the population. The downward trends in COVID-19 infections is now also very evident in younger age groups as they come forward for vaccinations and also adhere to the general measures to keep each other safe. pic.twitter.com/C4m9gxutGv— Stephen Donnelly (@DonnellyStephen) September 6, 2021
Mr Donnelly added that people need to continue to be safe and added that "Covid-19 hasn't gone away. The 14-day incidence rates for those aged between 35-44 is similar to that of those aged over 85".