Merrion Pharmaceuticals' chief executive Jonathan O'Connell will step down from the position at the end of June.
Mr O'Connell took over as CEO last May and has guided the company through its strategic review and restructuring.
Michael Donnelly, the current chairman at Merrion, will become executive chairman on June 30.
Mr O'Connell said that it had become clear that his job at the firm was nearing completion ''as the restructuring of the business is on a clear execution path with a sound financial footing''.
