The US Food and Drug Administration said this evening that officials had seized batches of GlaxoSmithKline diabetes drug Avandamet and the controlled-release antidepressant Paxil CR because of concerns over manufacturing quality.

The FDA said in a statement that the manufacturing practices for the two drugs failed to meet standards for safety, strength, quality and purity.

However, the agency said it was not aware of any harm to consumers and did not believe there was a significant health hazard.

Patients taking the two drugs were advised to continue taking their medication but talk to their doctor about possibly using alternative products until the manufacturing problems have been corrected.