The Department of Health has confirmed 1,185 new cases of Covid-19.
There are 292 people in hospital who have tested positive for the disease, a reduction of 17 since yesterday. Of these, 65 are being treated in intensive care, a rise of five.
There has been a total of 5,179 deaths related to Covid-19 notified in Ireland. This includes 24 deaths newly notified in the past week.
Chief Medical Officer Dr Tony Holohan said: "Covid-19 vaccines are providing very effective protection from severe illness and have fundamentally changed the risk profile of this disease.
"Since 1 April, approximately four out of every five people admitted to ICU and approximately three out of every four deaths with Covid-19 were not fully vaccinated.
"It remains vital that those who have not yet received a Covid-19 vaccine do so at the earliest opportunity.
"If you are fully protected through vaccination, then you can have confidence that your vaccination, and your continued adherence to the public health advice appropriate to each environment, is the best way you can protect yourself from Covid-19."
The 14-day incidence of the disease has reduced to just over 413 cases for every 100,000 people. The five day moving average is 1,212.
The counties with the highest rates are Monaghan, Donegal and Cavan.
There were 1,304 new infections reported in Northern Ireland alongside ten further deaths. Over the summer the death rate there was five times that of the Republic.
Northern Ireland has plans in place for a winter Covid-19 surge, according to First Minister Paul Givan.
Earlier today, the Chief Medical Officer told the Oireachtas Joint Committee on Health that Ireland is on track to proceed with the full lifting of Covid-19 restrictions next month.
Dr Holohan said this was because there are "a lot of encouraging trends" in age specific groups.
The committee also heard that there were 40 outbreaks of Covid-19 in schools last week.
It compares to just 12 outbreaks recorded in schools the week before last, but schools had only just reopened at that stage.
Meanwhile, two teacher unions have expressed "disappointment" at confirmation that the delivery of 10,000 C02 monitors to schools will be delayed for some weeks.
The ASTI union said the monitors constitute an important extra tool in the fight to ensure that Covid-19 transmission is minimised in schools and it is "disheartening in the extreme" that the roll-out has been delayed.
The Teachers' Union of Ireland described the delay as "extremely disappointing".