There has been one further Covid-related death and 408 new cases of the disease notified to the Department of Health.

The number of coronavirus patients in ICU is 33, one less than yesterday. There are 110 people in hospital with Covid-19 and there were nine additional hospitalisations in the past 24 hours.

A total of 4,919 people have died with Covid-19 in Ireland. The cumulative total number of cases since the pandemic began is 252,303.

Of the cases notified today: 205 are men, 202 are women and 77% are under 45 years of age. The median age is 31-years-old.

As of 6 May, 1,746,912 doses of Covid-19 vaccine have been administered in Ireland. 1,267,167 people have received their first dose while 479,745 people are full vaccinated with two doses.

The five day moving average of new cases is 406. This is a small decrease from one month ago when the five day moving average was 411.

The Chief Executive of the HSE has described the current hospital figures as "encouraging" when compared to the situation a few weeks ago.

"We now have a proven and winning combination, the vaccination programme and public support for public health measures," Paul Reid said on Twitter.

The majority of Covid patients in ICU are in St James' Hospital (8) and the Mater (5).

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There were no further Covid-related deaths reported today in Northern Ireland while 81 new positive cases were confirmed there.

Meanwhile, an immunologist has said people should moderate their alcohol intake so as to allow their immune system the best possible response upon receiving their Covid-19 vaccine.

Dr Annie Curtis is a senior lecturer at the Dublin-based Royal College of Surgeons University of Medicine and Health Science.

Speaking on RTÉ's Brendan O’Connor programme, Dr Curtis said people may have some side effects when receiving their vaccine, and so opening a bottle of bubbly on the day they get their jab "may not be the best option".

"Maybe wait for the celebrations when you reach full immunity," she said, adding that for most people, this is two weeks after their second jab.

"Moderation is key," urged Dr Curtis, adding that moderate alcohol consumption is fine.

"It’s fantastic we’re all getting vaccinated. There’s lots of things we can do to help our immune system to give it the best chance that it can to have the best response, and moderating alcohol is one of them."

Also today, the Department of Health announced that Austria and Italy are being removed from the list of designated states for mandatory hotel quarantine.