The Department of Health has been notified of 11 further deaths related to Covid-19 and 420 new cases.
The number of Covid patients in ICU is up two to 53.
There have now been a total of 4,831 Covid-19 related deaths in Ireland, with 242,819 confirmed cases.
Of the deaths reported today, three occurred in April, one in March, two in February and five occurred in January or earlier.
The median age of those who died was 88 and the age range was 77-94.
Of the cases notified today, 218 are men and 197 are women, with 74% under 45 years of age. The median age is 32.
The regional breakdown shows that there were 147 cases in Dublin, 41 in Meath, 33 in Donegal, 26 in Galway, 18 in Limerick and the remaining 155 cases are spread across all other counties.
As of 8am, there were 190 Covid-19 patients in hospital, with 12 additional hospitalisations in the past 24 hours.
Meanwhile, more than 1.21 million doses of a Covid-19 vaccine have now been administered to people in Ireland.
There have been 1,121,003 doses administered so far, with 789,526 people getting their first dose and 331,477 people fully vaccinated.
Tonight, it has been confirmed that Ireland will receive delivery of around 50,000 doses of the Pfizer vaccine every week for the next ten weeks.
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Another milestone in our COVID-19 Vaccination Programme— Stephen Donnelly (@DonnellyStephen) April 16, 2021
1 in 5 of those who can get a vaccine have now received a first dose. pic.twitter.com/mIUU3EQ5uY
The HSE has said that so far today an additional 17,600 people have registered to book vaccinations.
It said that 90% of this morning's bookings came through the online portal on HSE.ie with the remainder being made through the HSE-Live phone line 1850-24-1850.
Yesterday, more than 30,000 people registered for a Covid-19 vaccination after the online portal for 69-year-olds went live and others can continue to do so in the days and weeks ahead.
The HSE said that it would take three weeks to administer first dose vaccines to 65 to 69-year-olds and a further three weeks for the 60 to 64-year-olds, but that they will all be done by the end of May.
Elsewhere, there has been one further death of a patient who previously tested positive for Covid-19 in Northern Ireland.
Another 119 people have tested positive for virus in the last 24-hour reporting period.
This morning, there were 69 confirmed Covid-19 inpatients in hospital, nine of whom were in ICU.