Commercial vehicle sales figures for 2013 show that Ford sold 2,541 units, ahead of VW (2,079 units) and Renault (1,286 units).
A key part of Ford's van sales success is the iconic Transit, which has been a top seller in Ireland since it first arrived in 1965.
In 2013, Transit was again the top-selling model in Ireland with 1,402 units sold, ahead of the second-placed VW Caddy (1,328).
Eddie Murphy, Chairman and Managing Director, Ford Ireland, said: "Irish van drivers and fleet operators love our vans and it is heartening to see that we have secured the top spot again in the 2013 sales chart...
"Unlike the car market where there was a drop in sales, the commercial vehicle market managed to achieve modest growth of just 4.6% in 2013.
"It has long been accepted that this market is a good indicator of the general state of the economy, so on that basis, these figures tally with some commentators who have said the economy is due to improve during 2014.
"It is thanks to our great value tailored packages that Ford again took the lion's share of sales in the van market in 2013, outpacing the market growth to achieve an increase of 11.5% on our 2012 sales.
"In fact, there has never been a better time to buy a Ford commercial, with a low rate 3.9% APR available across the van range. And, unlike some of our competitors, we offer a five-year payback period, which helps to keep monthly repayments more manageable for cash-strapped operators."
Ford's line up of commercial vehicles will be expanded during 2014, with the imminent arrival of the new Transit Connect (International Van of the Year for 2014); the new Transit two-tonne arriving in April; and the compact new Ford Transit Courier van, which arrives in May.