Giuliana and Bill Rancic are expecting a baby via a gestational surrogate.
The couple, who married in 2007 will welcome their first child this summer.
Speaking to E! News Giuliana said: "We are so thrilled that our prayers have been answered."
Bill added: "We are absolutely ecstatic to be sharing this with everyone who has been following our journey."
It was previously reported that Giuliana was set to start fertility treatments in 2011 when she found out she had breast cancer.
The fifth season of Giuliana & Bill is currently airing on the Style Network.