With contract talks ongoing with the stars of the show, an upcoming episode of Grey's Anatomy features a storyline which would provide a reason for some of the characters to leave Seattle.

Warning: spoiler alert!

In a Q&A session with fans, TVLine.com's Michael Ausiello said: "I hear a late April episode will follow Alex (Justin Chambers), Meredith (Ellen Pompeo), Jackson (Jesse Williams), April (Sarah Drew) and Cristina (Sandra Oh) as they interview for fellowship positions at other hospitals around the country.

"Said hospitals are apparently wooing the quintet in anticipation of them passing their boards [assessments] - and they're wisely entertaining all of their options."