In the superficial world of high fashion, image is everything. Styles come and go, and the only constants are the superthin beauties who wear them. How can an ordinary girl - a slightly plump plain-Jane from Queens - possibly fit in?
If you took a moment to get to know Betty Suarez, you'd see how sweet, intelligent and hard-working she is. But few people do, because in the world of high fashion Betty is the oversized peg in the petite round hole. When publishing mogul Bradford Meade hands the reigns of Mode, the bible of the fashion industry, over to this son, Daniel, he specifically hires Betty as his son's new assistant - mostly because she's the only woman in NYC Daniel won't sleep with. Though this "player" is reluctant to accept her at first, Betty's indomitable spirit and bright ideas will eventually win him over. Neither of them really knows the ins and outs of the fashion world, but the two are a formidable team against those who will do anything to see them fall.
And they really are swimming with the sharks. Diva fashionista Wilhelmina Slater is incensed that Bradford Meade passed her over and promoted Daniel to the coveted job after the mysterious death of Mode's legendary editress, Fey Sommers. Wilhelmina, along with toadying assistant Marc and scheming receptionist Amanda, are out to sabotage Daniel and Betty any chance they get. Betty finds a friend in warm-hearted Christina, who works as the magazine's in-house seamstress and seems to know everything about everybody who works there.
Away from work, Betty's home life is far from glamorous. Dad Ignacio and her sister, Hilda, worry that she's just setting herself up for a fall, while nephew Justin encourages his aunt to dream big (even if he's aghast at her fashion sense). Nerdy boyfriend Walter, who unceremoniously dumped Betty, keeps turning up despite her attempts to get him to stay away.
"Ugly Betty" stars America Ferrera as Betty Suarez, Eric Mabius as Daniel Meade, Alan Dale as Bradford Meade, Tony Plana as Ignacio, Ana Ortiz as Hilda, Ashley Jensen as Christina, Becki Newton as Amanda, Mark Indelicato as Justin, Michael Urie as Marc, Kevin Sussman as Walter, Rebecca Romijn as Alexis Meade and Vanessa Williams as Wilhelmina Slater.