Sunderland v Manchester United (Sat 12:45)

Sunderland boss Martin O'Neill has doubts over David Vaughan and Stephane Sessegnon ahead of tomorrow's daunting Barclays Premier League clash with Manchester United.

Midfielder Vaughan returned early from international duty with Wales nursing a groin problem, while striker Sessegnon did not even meet up with Benin because of a similar injury, and both are being assessed.

However, defender Carlos Cuellar has been ruled out with the ankle problem he suffered in the 1-1 draw with Norwich and joins skipper Lee Cattermole (knee surgery) and striker Steven Fletcher (ankle ligaments), who will both miss the rest of the season, on the sidelines.

Manchester United have received a triple injury boost ahead of their Premier League trip to Sunderland.

Nani (hamstring), Phil Jones (ankle) and Paul Scholes (knee) have all recovered from their knocks.

All three could be involved at the Stadium of Light as United defend a 15-point lead at the top of the table, with Javier Hernandez and Antonio Valencia most likely to be excused due to their lengthy travels during the international break.

Sunderland squad: Mignolet, Westwood, Bardsley, Rose, O'Shea, Kilgallon, Bramble, Mangane, N'Diaye, Gardner, Colback, McClean, Larsson, Johnson, Vaughan, Sessegnon, Graham, Wickham.

Manchester United squad: De Gea, Lindegaard, Amos, Rafael, Smalling, Jones, Ferdinand, Vidic, Evans, Evra, Buttner, Giggs, Valencia, Scholes, Carrick, Cleverley, Anderson, Young, Kagawa, Nani, Welbeck, Rooney, Hernandez, Van Persie.

Arsenal v Reading

Arsenal will be without England duo Jack Wilshere (ankle) and Theo Walcott (hip/thigh) for tomorrow's Barclays Premier League clash against Reading at the Emirates Stadium.

Midfielder Abou Diaby is also absent after being ruled out for nine months with anterior cruciate ligament damage in his left knee.

Left-back Kieran Gibbs will be assessed after being laid low by a virus, but striker Lukas Podolski (ankle) and right-back Bacary Sagna (knee) should be available again, while goalkeeper Wojciech Szczesny and captain Thomas Vermaelen are eyeing recalls.

New Reading manager Nigel Adkins will have striker Pavel Pogrebnyak available again after a three-match suspension for tomorrow's game at Arsenal.

Former Gunners trainee Stuart Taylor is likely to again deputise for goalkeeper Adam Federici, who has been sidelined with an ankle injury, while attacking midfielder Jimmy Kebe continues to battle against a groin problem.

Forward Jason Roberts (hip) remains sidelined.

Arsenal Squad: Szczesny, Sagna, Vermaelen, Mertesacker, Monreal, Podolski, Cazorla, Arteta, Ramsey, Oxlade-Chamberlain, Giroud, Fabianski, Koscielny, Rosicky, Coquelin, Gervinho, Gibbs, Jenkinson, Arshavin.

Reading squad: Taylor, Mariappa, Pearce, Shorey, Kelly, McAnuff, Leigertwood, Karacan, Robson-Kanu, McCleary, Hunt, Pogrebnyak, McCarthy, Gunter, Harte, Akpan, Le Fondre, Morrison, Blackman, Kebe.

Manchester City v Newcastle United

Captain Vincent Kompany was Manchester City's chief concern ahead of their Barclays Premier League clash with Newcastle at the Etihad Stadium.

The defender, out for eight weeks with a calf injury, played for Belgium in midweek, much to manager Roberto Mancini's irritation.

Striker Sergio Aguero (knee) is fit to return after three games out while right-back Micah Richards and midfielder Jack Rodwell (hamstring) could be back early next month.

Newcastle boss Alan Pardew is facing a fresh injury crisis ahead of tomorrow's tough trip to play the champions.

Midfielder Cheick Tiote is out with a hamstring injury which could also sideline him for week's Europa League quarter-final trip to Benfica, while full-backs Mathieu Debuchy (hamstring), Davide Santon (thigh) and Massadio Haidara (knee) will also be missing.

Keeper Tim Krul (ankle) is back in training, but is not yet match-fit and Rob Elliot will keep his place in the team, while skipper Fabricio Coloccini (back) has returned to Tyneside from a break in Argentina, but is around three weeks away from playing again.

Manchester City squad: Hart, Pantilimon, Zabaleta, Kompany, Lescott, K Toure, Nastasic, Kolarov, Clichy, Milner, Nasri, Sinclair, Y Toure, Barry, Garcia, Silva, Tevez, Aguero, Dzeko, Razak.

Newcastle United squad: Elliot, Harper, Simpson, Taylor, Yanga-Mbiwa, Perch, Bigirimana, Cabaye, Anita, Gutierrez, Gosling, Marveaux, Obertan, Sissoko, Cisse, Gouffran, Ameobi, Campbell.

Southampton v Chelsea

Adam Lallana, Luke Shaw and Jos Hooiveld are all dealing with knocks ahead of Southampton's Barclays Premier League clash with Chelsea.

The trio will be assessed ahead of the St Mary's clash, although manager Mauricio Pochettino hopes they will all be fit to feature.

Vegard Forren could make his Saints debut, having started Norway's World Cup qualifier against Albania.

John Terry is available for Chelsea's trip to Southampton - but manager Rafael Benitez will select with one eye on Monday's FA Cup quarter-final against Manchester United.

Benitez said it is "impossible" for players to peak twice in 48 hours so some rotation of the side is inevitable and Terry, after a season disrupted by a knee injury, is only likely to start one of them.

Chelsea's interim manager reported a clean bill of health following the international break and he is hopeful that Ramires (Achilles) and Gary Cahill (knee) could be fit for Monday.

Southampton squad: Boruc, K Davis, Clyne, Richardson, Fox, Shaw, Yoshida, Fonte, Forren, Hooiveld, Ward-Prowse, Cork, Chaplow, Ramirez, Schneiderlin, S Davis, Lallana, do Prado, Puncheon, Mayuka, Lambert, Rodriguez.

Chelsea squad: Cech, Turnbull, Hilario, Ivanovic, Ferreira, Cole, Bertrand, Luiz, Terry, Cahill, Azpilicueta, Ramires, Oscar, Mata, Benayoun, Mikel, Moses, Lampard, Hazard, Marin, Torres, Ake, Ba.

Swansea v Tottenham

Chico Flores is set to return to the Swansea squad against Tottenham after seven weeks on the sidelines.

The Spaniard has not played since rupturing ankle ligaments against QPR at the start of February, but is close to making a comeback alongside Ashley Williams in defence.

Kemy Agustien (thigh) is unlikely to be involved while Neil Taylor is continuing to make good progress on his return from a broken and dislocated ankle.

Tottenham forward Gareth Bale is fit to face Swansea on Saturday despite suffering from illness on international duty.

Winger Aaron Lennon (hamstring and groin) and centre-back Michael Dawson (hamstring) have recovered from their respective injuries and are likely to start.

Defender Younes Kaboul is likely to be match fit in 10-15 days, but fellow knee injury victim Sandro is out for the rest of the season.

Swansea squad: Vorm, Bartley, Flores, Tate, Williams, Britton, Michu, Hernandez, Dyer, Cornell, Lamah, Routledge, Monk, Shechter, Moore, De Guzman, Tiendalli, Rangel, Ki, Tremmel, Agustien, Davies.

Tottenham squad: Lloris, Friedel, Walker, Naughton, Gallas, Dawson, Caulker, Vertonghen, Assou-Ekotto, Lennon, Holtby, Livermore, Dembele, Carroll, Parker, Huddlestone, Sigurdsson, Bale, Dempsey, Defoe, Adebayor, Coulthirst.

West Ham v West Bromwich Albion

West Ham captain Kevin Nolan has recovered from a toe injury and is available for tomorrow's home game against West Brom.

Midfielder Joe Cole returns following a month-long hamstring injury lay-off, but Mark Noble (shoulder) is unavailable.

Defender George McCartney is also fit after nearly four months out with a knee problem, but back-up goalkeeper Raphael Spiegel (finger) is out so Stephen Henderson has been recalled from his loan at Ipswich.

Midfielder James Morrison is West Brom's major fresh injury concern ahead of tomorrow clash with West Ham.

Morrison suffered a hamstring injury during the goalless draw against Stoke a fortnight ago and was forced to withdraw from international duty with Scotland.

Head coach Steve Clarke confirmed striker Peter Odemwingie was part of the squad, despite his latest Twitter attacks against the Baggies which are being investigated internally.

West Ham squad: Jaaskelainen, Henderson, Reid, Tomkins, Collins, Pogatetz, McCartney, O'Brien, Demel, Jarvis, Diame, O'Neil, Nolan, J Cole, Collison, Taylor, Diarra, C Cole, Vaz Te, Carroll, Maiga, Chamakh.

West Brom squad: Foster, Myhill, Daniels, Reid, Jones, Olsson, McAuley, Tamas, Ridgewell, Popov, Dorrans, Mulumbu, Yacob, Brunt, Morrison, Thomas, Lukaku, Long, Fortune, Odemwingie, Rosenberg, Sawyers, Brown.

Wigan v Norwich

Wigan boss Roberto Martinez is hoping striker Callum McManaman will be fit for tomorrow's key Barclays Premier League clash with Norwich at the DW Stadium.

The 21-year-old aggravated an ankle injury during the 2-1 victory over Newcastle two weeks ago - a match in which he made headlines for the wrong reasons with a knee-high challenge on Massadio Haidara for which he escaped punishment.

Martinez is also worried about overplaying Antolin Alcaraz following his return from six months out with a groin injury, while he must decide whether to recall goalkeeper Ali Al Habsi and captain Gary Caldwell after two wins in a row without them.

With goalkeeper Mark Bunn suspended after being sent off against Sunderland, Norwich manager Chris Hughton has confirmed Lee Camp will start in goal for the Canaries at Wigan.

First choice goalkeeper John Ruddy returned to training this week following surgery on a thigh problem but will require several reserve games before being considered for first-team action.

Meanwhile, midfielder Alexander Tettey is back in contention after recovering from a knee injury and Russell Martin (hamstring) is fit again after pulling out of the Scotland squad.

Anthony Pilkington (hamstring) could be back next weekend after a three-week lay-off.

Wigan squad: Al Habsi, Boyce, Caldwell, Alcaraz, Scharner, Figueroa, Beausejour, Gomez, Maloney, Espinoza, McCarthy, McArthur, Stam, McManaman, Kone, Di Santo, Henriquez, Golobart, Robles, Lopez.

Norwich squad: Camp, R Martin, Bassong, Barnett, Garrido, Snodgrass, Johnson, E Bennett, Turner, Jackson, Holt, Becchio, Howson, Hoolahan, Fox, Tettey, R Bennett, Smith, Steer, Whittaker, Kamara.

Everton v Stoke (Sat 5:30pm)

Everton could welcome back goalkeeper Tim Howard and defender Phil Jagielka for the clash against Stoke at Goodison Park.

Howard (back) and Jagielka (ankle) have both missed the Toffees' last three games.

Midfielders Marouane Fellaini and Steven Pienaar are both beginning two-match suspensions and defender Tony Hibbert (calf) is still sidelined.

Stoke have Robert Huth back available for the trip to Everton after the defender completed a three-match suspension.

Huth, who served the ban after accepting a violent conduct charge from the Football Association relating to an incident in the Potters' 1-0 defeat at Fulham last month, is expected to make an immediate return to the starting XI, linking up once again with his centre-half partner Ryan Shawcross.

Stoke boss Tony Pulis looks set to have a full squad to choose from for the fixture.

Everton squad: Howard, Mucha, Distin, Heitinga, Baines, Coleman, Neville, Oviedo, Naismith, Hitzlsperger, Osman, Jelavic, Anichebe, Vellios, Gibson, Mirallas, Duffy, Barkley.

Stoke squad: Begovic, Sorensen, Cameron, Wilkinson, Huth, Shawcross, Whelan, Nzonzi, Walters, Kightly, Etherington, Jones, Whitehead, Crouch, Jerome, Adam, Palacios, Shotton, Shea, Wilson, Owen.

Aston Villa v Liverpool (Sun 1:30pm)

Aston Villa manager Paul Lambert will welcome back a quartet of players but has fitness concerns over two others for the home Barclays Premier League clash with Liverpool on Sunday.

Darren Bent (foot), Nathan Baker (head) and Karim El Ahmadi (ankle) are all in contention to face the Reds. Fabian Delph is available after a two-game suspension.

Ciaran Clark and Brett Holman suffered shoulder and hamstring injuries while on international duty and will be assessed over the weekend.

Liverpool have goalkeeper Jose Reina and defender Jamie Carragher fit again for Sunday's trip to Aston Villa.

The pair missed the defeat at Southampton almost a fortnight ago with calf and shin injuries respectively but have subsequently recovered.

All players have returned from international duty without reporting any problems so it leaves only Fabio Borini and Joe Allen (both shoulder) and Martin Kelly (knee) absent.

Aston Villa squad: Guzan, Given, Lowton, Vlaar, Clark, Lichaj, Stevens, Baker, Bennett, Sylla, El Ahmadi, Ireland, Westwood, Dawkins, N'Zogbia, Bannan, Holman, Benteke, Agbonlahor, Bent, Bowery, Weimann.

Liverpool squad: Reina, Johnson, Carragher, Agger, Enrique, Lucas, Gerrard, Henderson, Coutinho, Suarez, Sturridge, Jones, Wisdom, Skrtel, Shelvey, Sterling, Downing, Suso, Ibe.

Fulham v Queens Park Rangers (Mon 8pm)

Mahamadou Diarra remains Fulham's only absentee for Monday's visit of basement club QPR to Craven Cottage.

The Mali midfielder, out of contract at the end of the season, will not play again before then after it was discovered his troublesome left knee will require a third operation.

Manager Martin Jol has no other injury concerns as his side seek to build on a four-match unbeaten run.

QPR manager Harry Redknapp has Bobby Zamora back fit.

Zamora, the former Fulham striker, used the international break to overcome an ankle injury and a dose of the flu to be in contention for the west London derby.

Redknapp reported a clean bill of health following the international window and he must decide whether to recall the mercurial Moroccan Adel Taarabt to the side.

Fulham squad: Schwarzer, Somogyi, Etheridge, Riether, Hangeland, Hughes, Senderos, Riise, Dejagah, Baird, Karagounis, Kacaniklic, Frimpong, Davies, Richardson, Frei, Mesca, Enoh, Berbatov, Sidwell, Duff, Ruiz, Emanuelson, Rodallega, Petric.

QPR squad: Cesar, Green, Onuoha, Hill, Samba, Mbia, Fabio, Traore, Granero, Diakite, Hoilett, Park, Derry, Taarabt, Jenas, Townsend, Wright-Phillips, Mackie, Remy, Bothroyd, Zamora.