SATURDAY 15 FEBRUARY
SUNDERLAND v SOUTHAMPTON 12.45pm
Wes Brown begins his two-match suspension, after he was sent off for a professional foul on Shane Long last weekend.
Striker Ignacio Scocco will make his debut for the club, while there will be a chance too for midfielder Emanuele Giaccherini, but defender Carlos Cuellar (hip) will be given another week and frontman Steven Fletcher (Achilles) and goalkeeper Keiren Westwood (shoulder) remain on the sidelines.
Southampton have no fresh injury concerns.
Saints returned from Tuesday's 1-0 win at Hull unscathed and assistant manager Jesus Perez suggests there will not be wholesale changes at the Stadium of Light.
Dejan Lovren and Gaston Ramirez suffered ankle ligament damage in the league meeting between the sides a month ago and, despite rehabilitation going well, remain absent.
Sunderland squad: Mannone, Ustari, Celustka, Alonso, Bardsley, O'Shea, Vergini, Roberge, Bridcutt, Cattermole, Gardner, Ki, Giaccherini, Johnson, Larsson, Ba, Mavrias, Colback, Altidore, Borini, Scocco.
Southampton squad: Boruc, K Davis, Gazzaniga, Clyne, Chambers, Shaw, Targett, Hooiveld, Fonte, Yoshida, Wanyama, Schneiderlin, Cork, Lallana, Isgrove, Ward-Prowse, Do Prado, S Davis, Reed, Rodriguez, Lambert, Gallagher.
CARDIFF v WIGAN 3pm
Kenwyne Jones and Fabio are cup-tied for Cardiff.
The striker and full-back miss out having featured for Stoke and Manchester United earlier in the competition, while the Bluebirds are waiting for United to confirm Wilfried Zaha's availability; the winger was an unused substitute in the Red Devils' third-round defeat to Swansea.
Spanish defender Juan Cala will make his debut while Ole Gunnar Solskjaer may opt to hand starts to the Norwegian trio of Magnus Wolff Eikrem, Mats Moller Daehli and Jo Inge Berget. Craig Bellamy is suspended.
Cardiff squad: Marshall, Taylor, Caulker, Turner, Whittingham, Medel, Campbell, Kim, Smith, Eikrem, Noone, Gunnarsson, Mutch, Cowie, McNaughton, Theophile-Catherine, Daehli, Lewis, Berget, Zaha, Cala.
MANCHESTER CITY v CHELSEA 5.15pm
Manchester City midfielder Samir Nasri is back in contention after five weeks out with a knee injury.
Fellow midfielder Javi Garcia is also available again after a muscle strain but top scorer Sergio Aguero (hamstring), defender Matija Nastasic (knee) and another midfielder in Fernandinho (muscle injury) are still out.
Manager Manuel Pellegrini has not revealed whether he will persist with his usual cup policy of playing second-choice goalkeeper Costel Pantilimon ahead of Joe Hart.
City squad: Hart, Pantilimon, Zabaleta, Richards, Kompany, Demichelis, Lescott, Boyata, Clichy, Kolarov, Milner, Navas, Nasri, Toure, Garcia, Rodwell, Negredo, Jovetic, Dzeko, Lopes.
SUNDAY 16 FEBRUARY
EVERTON v SWANSEA 1.30pm
On-loan striker Lacina Traore is set to make a delayed Everton debut after being denied his Goodison Park bow by the postponement of Wednesday's match against Crystal Palace.
The Monaco forward has been named on the bench for the last two games, one of which did not go ahead because of high winds, but is likely to be given a run-out this Sunday.
Fellow on-loan striker Romelu Lukaku is still a week away from fitness while defender Antolin Alcaraz has returned to training but will not be match-ready until the start of March.
Garry Monk will make a late decision on Michu's fitness. The Spaniard was not risked in the games against Cardiff and Stoke.
David Ngog and Marvin Emnes are both cup-tied having featured for Bolton and Middlesbrough respectively in earlier rounds of the competition.
Swansea squad: Vorm, Amat, Taylor, Flores, Williams, Britton, Shelvey, Michu, Bony, Hernandez, Dyer, Cornell, Lamah, Routledge, Tiendalli, De Guzman, Canas, Rangel, Pozuelo, Tremmel, Vazquez, Richards.
Everton squad: Howard, Coleman, Jagielka, Distin, Baines, Barry, McCarthy, Mirallas, Barkley, Pienaar, Naismith, Robles, Hibbert, Stones, McGeady, Osman, Deulofeu, Traore.
ARSENAL v LIVERPOOL 4pm
Arsenal midfielder Santi Cazorla is doubtful because of illness, but Mathieu Flamini returns from a three-game suspension.
With one eye on next week's Champions League clash against Bayern Munich, Gunners manager Arsene Wenger could rest some players like striker Olivier Giroud and goalkeeper Wojciech Szczesny.
Defender Thomas Vermaelen (knee) continues his recovery, while midfielder Aaron Ramsey (thigh) and deadline-day loan signing Kim Kallstrom (back) are also not fit. Abou Diaby and Theo Walcott are long-term absentees with their respective knee injuries.
Liverpool defender Daniel Agger could be pushing for Kolo Toure's place after making his comeback from a calf injury in midweek.
The match probably comes too early for full-back Glen Johnson, who is more likely to be fit for next week after ankle and groin problems.
Liverpool squad: Mignolet, Flanagan, Skrtel, Agger, Cissokho, Gerrard, Henderson, Sterling, Coutinho, Sturridge, Suarez, Jones, Kelly, Toure, Allen, Alberto, Aspas, Moses, Ibe, Teixeira.
Arsenal squad: Fabianski, Jenkinson, Mertesacker, Koscielny, Monreal, Flamini, Oxlade-Chamberlain, Wilshere, Gnabry, Rosicky, Podolski, Szczesny, Giroud, Gibbs, Sagna, Ozil, Sanogo, Arteta, Bendtner.
MONDAY 17 FEBRUARY
Brighton v HULL 7.45pm
Sone Aluko is in line for his first start in four months as Hull visit Brighton.
Aluko has made two substitute appearances in the league since returning from an Achilles injury and is expected to start up front with Shane Long and Nikica Jelavic cup-tied.
Paul McShane is out for six months with an ankle injury, goalkeeper Allan McGregor has completed a three-game ban and the likes of George Boyd, Yannick Sagbo, Robert Koren, Abdoulaye Faye and Robbie Brady will all be hoping to return to the starting XI.
Hull squad: McGregor, Harper, Davies, Bruce, Huddlestone, Elmohamady, Meyler, Brady, Quinn, Livermore, Boyd, Figueroa, Fryatt, Koren, Sagbo, Aluko, Jahraldo-Martin, Henderson.