Arsenal v West Brom (Saturday)
Arsenal will be without forwards Lukas Podolski (hamstring) and Theo Walcott (calf) against West Brom.
Defender Bacary Sagna (foot) is a major doubt, but Laurent Koscielny (thigh) is definitely out.
West Brom head coach Steve Clarke has virtually a full squad to choose from with goalkeeper Ben Foster the only absentee as he continues his rehabilitation after a second groin operation. Boaz Myhill again deputises.
Aston Villa v Stoke (Saturday)
Aston Villa winger Charles N'Zogbia has returned to training after a six-week absence with a knee problem but may not feature against Stoke.
Skipper and centre-back Ron Vlaar remains a major doubt with a calf problem which ruled him out of the last two games with Reading and QPR.
Stoke are hopeful striker Peter Crouch will be able to return having lost some teeth in a collision with Newcastle's Fabricio Coloccini.
Southampton v Reading (Saturday)
Gaston Ramirez will be available to face Reading despite spending the week in Uruguay on on compassionate leave.
Richard Chaplow and Frazer Richardson are back in training after injury, although the latter is not yet ready for a first-team return.
Reading striker Pavel Pogrebnyak is a doubt after sustaining an unspecified injury while on reserves duty, while Danny Guthrie should return from a thigh problem.
Sunderland v Chelsea (Saturday)
Defender John O'Shea and striker Steven Fletcher are both in contention to face Chelsea.
O'Shea is the more likely to feature having trained this week following a calf injury.
Midfielder Frank Lampard will return from his calf injury at the Stadium of Light. Defender John Terry and striker Daniel Sturridge are still sidelined with knee and hamstring problems respectively.
Swansea v Norwich (Saturday)
Swansea manager Michael Laudrup will not rush Michel Vorm and Pablo Hernandez back into his starting line-up against Norwich.
Goalkeeper Vorm is back in training following a groin injury but is not ready to return, while Hernandez is still struggling with a thigh problem.
Goalkeeper John Ruddy has undergone a thigh operation and faces up to three months out, while defender Michael Turner (shoulder) and striker Harry Kane (metatarsal) are also missing.
Wigan v QPR (Saturday)
Wigan are set to be without four central defenders against QPR. Antolin Alcaraz (groin) and Ivan Ramis (hamstring) are injured while captain Gary Caldwell and Maynor Figueroa are both suspended.
Goalkeeper Julio Cesar is a QPR doubt as he is still struggling with the groin injury he suffered at Sunderland two weeks ago.
Stephane Mbia and Samba Diakite have recovered from the neck and ankle injuries. Bobby Zamora (hip) and Andrew Johnson (knee) remain sidelined.
Everton v Tottenham (Sunday)
Everton could have Kevin Mirallas and Seamus Coleman available to face Tottenham. Toffees boss David Moyes says forward Mirallas, who has missed four games due to a hamstring injury, and full-back Coleman, sidelined for three by an unspecified problem, have "outside chances" of featuring. Victor Anichebe (hamstring) and Phil Neville (knee) remain on the casualty list.
Tottenham defender Michael Dawson has only a slim chance of recovering from his hamstring injury, while winger Gareth Bale is out with a hamstring problem.
Man City v Man Utd (Sunday)
David Silva (hamstring) could return for Sunday's derby against Manchester United. Midfielder James Milner (hamstring) and left-back Gael Clichy (ankle) are also hoping to prove their fitness while midfielder Yaya Toure returns after his midweek European suspension. Defender Aleksandar Kolarov (ankle) has been ruled out, along with Micah Richards (knee).
Manchester United are waiting on the results of a scan on Tom Cleverley's calf injury before finalising his side. Antonio Valencia (hip) and Nani (hamstring) are definitely out.
West Ham v Liverpool (Sunday)
West Ham welcome Yossi Benayoun back into the squad. The former Reds midfielder missed the 3-1 win over Chelsea as he was ineligible to appear against his parent club.
Ricardo Vaz Te (shoulder), Alou Diarra (thigh) and Jack Collison (knee) are all definitely out.
Liverpool's Luis Suarez is suspended after accumulating five bookings. Manager Brendan Rodgers has played midfielder Jonjo Shelvey in a 'false nine' position before and could do so again.