Liverpool may have to make do with one recognised striker until the January transfer window after learning that Fabio Borini had fractured his foot training with Italy's U-21s on Thursday.
The Italian Football Federation confirmed that the 21-year-old suffered the injury to his right foot while preparing for the match against Sweden.
Borini, signed from Roma in July, could be set for a lengthy absence. That would leave Uruguayan Luis Suarez as Liverpool's sole fit striker as they try to kick-start their season.
Borini's injury highlights the paucity of options available to manager Brendan Rodgers, who allowed towering striker and club record signing Andy Carroll to join West Ham United on loan in the summer.
Rodgers was unable to replace Carroll before the transfer window closed.
Liverpool have endured one of their worst starts to a top flight season, winning just one of their opening seven Premier League matches in which they have scored only nine times.