Rio Ferdinand and Patrice Evra will be rested for Manchester United's Champions League encounter with Braga at Old Trafford tomorrow.
Ferguson has also told a press conference that he has resolved his dispute with Ferdinand over the defender's failure to wear a T-shirt supporting the Kick It Out anti-racism campaign group on Saturday.
Following Ferdinand's defiance over the issue Ferguson had said the 33-year-old would be "dealt with".
The pair have seemingly resolved their differences though and Ferdinand trained at Carrington this morning ahead of tomorrow night's Champions League tie at Old Trafford.
Ferguson said: "There is no issue. There was a communication problem. But it has been resolved."
The United manager also revealed he had decided to rest Ferdinand and Evra ahead of the Premier League clash with leaders Chelsea on Sunday.
"He and Patrice Evra will not play. There is a big game at Chelsea on Sunday. They will be the two main changes tomorrow."
But with Chris Smalling still out with a broken metatarsal the defensive options are limited for Ferguson and his decision not to play Ferdinand could see Jonny Evans paired with rookie Scott Wootton.
Ashley Young could return from a knee injury suffered in August after taking part in training.
United have started their European campaign with a 100 per cent record following victories over Galatasaray and Cluj.
Provisional squad: De Gea, Lindegaard, Rafael, Ferdinand, Evans, Wootton, Evra, Buttner, Valencia, Nani, Powell, Cleverley, Carrick, Anderson, Scholes, Fletcher, Giggs, Young, Kagawa, Van Persie, Rooney, Hernandez, Welbeck.