Shamrock Rovers will meet Shelbourne in the quarter-finals of the FAI Cup after the draw was made on Monday.
The Dublin derby is the highlight of the draw with the Hoops looking to end a barren spell in the cup competition.
St Patrick’s Athletic will take on Drogheda United in another mouth-watering tie with both sides riding high in the league.
Bohemians host Dundalk in a third all-Premier Division tie, while Derry City await the winners of the twice postponed Waterford United and Mervue United tie.
Matches will be played on the weekend of 16 September.
Shelbourne v Shamrock Rovers
Bohemians v Dundalk
St Patrick’s Athletic v Drogheda United
Derry City v Waterford United/Mervue United