Ireland have been rocked by a triple blow as Mike McCarthy, Sean O'Brien and Dave Kearney have all been ruled out of the rest of the Six Nations.
McCarthy's season is over after a consultation with a specialist, while O’Brien and Kearney will not feature in Schmidt's plans for the rest of the tournament.
O'Brien limped out of last week's bruising defeat to France with a hamstring injury, while McCarthy [concussion] and Kearney [shoulder] were also casualties of a Paris defeat that has had severe ramifications for the Ireland camp.
Keith Earls, who was concussed in the opening game against Wales, trained fully with the Irish squad yesterday and today.
Schmidt lamented the pile-up of injuries in the wake of the loss at the Stade de France, and the confirmation of the trio's lengthy absences will be a bitter pill to swallow.
Ireland face England at Twickenham next Saturday, before finishing their campaign with home games against Italy and Scotland.