Italy expect to have flanker Mauro Bergamasco and prop Martin Castrogiovanni available for Saturday's RBS 6 Nations match against Scotland in Rome (1.30pm Irish time).
Both players missed Monday's training session and are undergoing treatment to recover from their respective injuries.
Castrogiovanni is struggling with a heel problem in his right foot while Bergamasco sustained a knock on his left thigh in his team's 30-10 loss to France in Paris on 9 February.
"We are approaching this week with focus and calmness," Italy team manager Luigi Troiani said on federugby.it. "We are aware that the expectations regarding our home game against Scotland are high.
"We are coming off two games in which we have displayed good things but struggled to be consistent.
"This is something we will have to improve on against Scotland.
"Regarding Castrogiovanni and Bergamasco, we are looking to have both of them back in training with the rest of the group on Thursday."
The Azzurri, coached by Jacques Brunel, are looking for their first win of the campaign this weekend after losing 23-15 to Wales in Cardiff in their Six Nations opener and falling in Paris to France a week later.
Italy have already sold 120,000 tickets for their home games - against Scotland and against England on 15 March - at Rome's Stadio Olimpico.