Newport Gwent Dragons back Hallam Amos will make his Wales debut in Friday night's clash against Tonga at the Millennium Stadium.
Stockport-born Amos, 19, who moved to Wales at the age of four, is among 11 changes from the side that claimed a record 40-6 victory against Argentina three days ago.
The four survivors from that Pumas clash are full-back Leigh Halfpenny, wing George North, prop Rhodri Jones and flanker Justin Tipuric in a team captained by number eight Ryan Jones.
Wales team to play Tonga: L Halfpenny; G North, O Williams, H Amos; J Hook, L Williams; P James, K Owens, Rhodri Jones, L Charteris, I Evans, A Coombs, J Tipuric, Ryan Jones (capt).
Replacements: E Phillips, R Bevington, S Lee, D Lydiate, S Warburton, R Williams, R Priestland, J Williams.