Former Godolphin racing manager Simon Crisford is to join the training ranks, subject to approval from the British Horseracing Authority.
Crisford, who worked for Sheikh Mohammed's operation since its inception in 1994, left his position to take up the role of global racing advisor to the Maktoum family after a number of changes to the organisation in February.
He is to start out in his new career by renting out part of Clive Brittain's Carlburg Stables in Newmarket.
"I am very excited to be setting up my own training business," said Crisford.
"It is something I have always wanted to do and I am delighted to have the opportunity to realise that ambition now.
"Clive Brittain has very kindly agreed to rent me some boxes and, subject to BHA approval, I will be operating from his isolation yard at Carlburg Stables."
Crisford will continue his consultancy work as international racing advisor to the Maktoum family and their associates.
Crisford, 52, had previously worked as assistant trainer to John Dunlop and Mark Prescott and also has close associations with the likes of Saeed bin Suroor and Andre Fabre, two of Godolphin's main trainers.
"My immediate plans are to start structuring my new business and to recruit some talented staff,” said Crisford.
"I will be working hard to build a team of horses and to put everything in place so that we are up and running in time for next season.
"I will be operating as a public trainer but I also hope that the Maktoum family might consider supporting me."
Crisford's role changed at Godolphin on the back of an internal investigation by John Stevens into former trainer Mahmood Al Zarooni, who was warned off for eight years.
The investigation concluded Al Zarooni acted alone in giving 11 horses in his stables banned substances, but that "stronger management, clearer accountability and better internal communication within the equestrian organisation" were needed.
As a result, the role of racing manager within the organisation no longer existed.