Al Kazeem will face a maximum of eight rivals in Wednesday's Juddmonte International Stakes at York.
Roger Charlton's five-year-old has been one of the success stories of the season with wins in the Tattersalls Gold Cup, Prince Of Wales's Stakes and Eclipse and he will aim to add another Group One to his growing list of achievements.
Richard Hannon has left in Sussex Stakes winner Toronado, who would be stepping up to 10 furlongs for the first time if he is allowed to take his chance.
Aidan O'Brien has a host of top-class options, including last year's dual Derby winner Camelot, who has finished behind Al Kazeem twice already this season.
The Ballydoyle handler also has the option of running Queen Anne winner Declaration Of War, Epsom Derby hero Ruler Of The World and one of last year's leading juveniles Kingsbarns, although he is also entered in the Neptune Investment Management Great Voltigeur Stakes on the same day and is yet to run this term.
Jim Bolger's Irish Derby winner Trading Leather and Michael Stoute's Royal Ascot winner Hillstar are other three-year-olds engaged while James Toller's Rewarded is the final contender.
As expected, French runner Cirrus Des Aigles will not be making the trip to England following his defeat last weekend.