Overdose's bubble burst at Haydock as Irish challenger Sole Power claimed victory in the betfred.com Temple Stakes.
The Hungarian superstar arrived on Merseyside having won 15 of his 16 starts on the continent, earning the nickname 'The Budapest Bullet' for his scintillating displays of speed from the front.
But injury problems have plagued his career for the last couple of years and although a minor-race victory in Germany last month suggested the firepower remained, this was his first try back in the big time.
Having overcome a slightly tardy start, Jozef Roszival's six-year-old looked content bouncing along out in front for the first half of the five-furlong contest.
But jockey Andreas Suborics was sending out the distress signals soon after. He eventually faded and passed the post a disappointing seventh.
Edward Lynam's Sole Power (8-1) was a shock 100-1 winner of the Nunthorpe at York last year and many sceptics had that down as a fluke.
But ridden by South African Keagan Latham, the son of Kyllachy silenced the doubters by showing a brilliant burst of speed when it mattered to collect Group Two honours by three-quarters of a length from Kingsgate Native.
Lynam said: ‘Anyone who thought he fluked the Nunthorpe can think again.
‘There were the winners of the last four Nunthorpes in that race today and luckily it was our turn, which is the way with sprinters.
‘Keagan gave him a lovely ride and I'm delighted the horse has shown the doubters.
‘He'll go to the posh place (Royal Ascot) for the King's Stand, but the race we want to win again is the Nunthorpe.’
Suborics felt conditions were too fast for his mount following his injury problems.
‘He just moved too high on the ground and I think he would prefer it softer now after his problems,’ said the jockey.
‘The ground felt very fast and at halfway I was worried as his action was getting higher and higher.
‘It is not the horse's fault he has had problems, but he has not been able to show his best today. I think he deserves another chance on softer ground.’
Anne Of Kiev (11-1) defied joint-top weight to claim the Listed Betfred The Bonus King Stakes.
Jeremy Gask's six-year-old scythed through the field passing the one-furlong marker to win going away under Pat Cosgrave, coming home two lengths ahead of Dubai Media.
Gask said: ‘We'd thought about running her in the Temple Stakes but she disappointed at Nottingham last time when I think the ground was a bit loose.
‘She's done it well today and we'll play it by ear as to where we go next.’
Sagramor (15-2) motored home in the hands of Nicky Mackay to win the Betfred Silver Bowl Handicap for Hughie Morrison.
‘It's fantastic for the owners, who also bred him. That is what racing is all about,’ said Morrison.
‘He's a proper little horse but to be honest, I never thought he would be good enough to win a competitive handicap like this.
‘The plan has always been to go to Royal Ascot for the Britannia Stakes and that is where he'll go next.’
Brown Panther could represent Manchester United striker Michael Owen at Royal Ascot after securing his third victory from four starts in the Betfred ‘Both Teams Score, Goals Galore!’ Handicap.
Patiently ridden by Richard Kingscote, the 2-1 favourite was the last horse on the bridle and quickened up smartly when asked the question to beat Reflect by a length and three-quarters.
Winning trainer Tom Dascombe, securing his fourth winner at the Merseyside track this week, said: ‘It's been a good few days.
‘This is a nice horse and he's done it really well. I'd imagine he'll go to Royal Ascot now for the King George V Handicap.
‘It's fantastic for Michael. Unfortunately he couldn't be here today, but I know he'll have been watching and he'll be absolutely loving it.’
The Richard Guest-trained Dickie Le Davoir (20-1) finished with a wet sail under Robert Butler to deny favourite Karaka Jack by a neck in the Betfred Text ‘Fred’ To 89660 Handicap.
Guest's assistant, Steven Arnold, said: ‘Robert has given him a great ride and gets on really well with the horse.
‘He said he always thought he was going to get there - he doesn't really get going until the last 100 yards.
‘I'm not sure what the plan is - today was the day.’
David Simcock's Tariq Too (7-2) also impressed in the Betfred Dennis Dootson 60th Birthday Handicap.
Neil Callan was found guilty of careless riding on the unplaced Ocean Legend and handed a three-day suspension.
The concluding Betfred Bundles Handicap went to Paul Midgley's 16-1 shot Dazeen.