Anthem Alexander takes on the boys when she goes for Group One honours in the feature race at the Curragh, the Keeneland Phoenix Stakes.
Eddie Lynam's filly was an impressive winner of the Queen Mary Stakes at Royal Ascot and it was made all the more meritorious by the runner-up, Tiggy Wiggy, blitzing the field in a hot sales race at Newbury since.
Another prominent Royal Ascot runner is in opposition, as Cappella Sansevero was second in the Coventry Stakes, while Aidan O'Brien's challenge is headed by The Great War, with Dick Whittington, I Am Beautiful and War Envoy the able back-up.
The Group Three Phoenix Sprint Stakes gives the speedballs a chance to showcase their talents, with Greenlands Stakes runner-up Maarek heading the weights.
Russian Soul, third in a Listed race at Tipperary on Friday, opposes, along with the likes of An Saighdiur and British raiders Hamza and Rocky Ground.
O'Brien's John F Kennedy was quoted for next year's Classics before setting foot on a racecourse so will be expected to improve on his opening second-placed finish in the Irish Stallion Farms EBF Maiden at 2.35pm.
He faces some tough opposition though, headed by Portage, who caught the eye when second on his debut, while Intransive makes his debut for Dermot Weld with a wealth of winners among his siblings.
Recent winners Toogoodtobetrue and Vocal Nation pit their talents against Galway second Tamadhor in the Loder EBF Fillies Race, though perhaps of more interest is John Oxx's newcomer Pour Deux.
Out of a close relative to Epsom Derby hero Pour Moi, the Dansili filly has been pitched into competitive company for her first outing.
Fix It and Nancy Rose bid to follow up last-time successes in the Gabriel Curran Memorial Handicap, while the Kerry Businesswomen's Network Handicap sees Willie Mullins call on the services of Joseph O'Brien to ride Roscommon scorer Ashjar.