Lammtarra, the unbeaten winner of the Derby, King George and Prix de l'Arc de Triomphe in 1995, has died at the age of 22.
Trained by the late Alex Scott as a two-year-old, the English horse won the Derby at Epsom in the care of Saeed bin Suroor after Scott was tragically murdered in September 1994, a month after the son of Nijinsky had won the Washington Singer at Newbury.
He raced in the name of Sheikh Mohammed's nephew Saeed Maktoum al Maktoum as a juvenile before being part of Godolphin in his Classic season, which saw him add the two all-aged middle-distance championships of Europe to his Epsom laurels.
The chestnut passed away in his sleep at Dalham Hall Stud in Newmarket on Sunday following a short illness.
From just four starts, Lammtarra earned over £1.25million in winning prize money.
Bin Suroor told Press Association Sport: "It is very sad. He is one of the best horses I have trained.
"He won the Epsom Derby, the King George and the Arc. Very few horses have managed to win those three races.
"He was a great horse, it is sad to lose him and we will miss him, but he will be remembered forever."