Richard Hannon's Sky Lantern is among just five still engaged in the Etihad Airways Falmouth Stakes at Newmarket on Friday.
Winner of the 1000 Guineas on the Rowley Mile, she bettered that performance when streaking away with the Coronation Stakes at Royal Ascot.
That performance indicated to her handler that she was ready for a crack at older horses.
She is likely to meet John Gosden's Elusive Kate, who made a satisfactory comeback in the Queen Anne behind Declaration Of War.
David Wachman's Duntle, a winner at the last two Royal Ascot meetings, will aim for Group One glory having lost the Matron Stakes in controversial circumstances last season.
Last year's race was won by Alain de Royer-Dupre's Giofra and she could try for a repeat.
Speaking at Sandown on Friday the French handler said: "I might run Giofra in the Falmouth next week. She's very well, but she needs good ground."
The field is completed by William Muir's Purr Along, eighth on her return to action in the Coronation.