European shares ended flat today, coming off lows after British Prime Minister Theresa May provided some clarity on her country's plans to leave the European Union.

In London £27 billion was wiped off the FTSE 100, after Ms May used a major speech to detail priorities ahead of Brexit negotiations.

The index closed 1.46% lower at 7,220, while all of the major euro zone markets also fell.

The CAC in Paris dropped 0.46% to 4,859, and in Frankfurt the DAX fell 0.04% to 11,557.

In Dublin the ISEQ lost 0.12% to 6,570. Kenmare and AIB were among the best performing shares, while Datalex and Kerry Group were both down.

Meanwhile, in the US stocks have fallen, weighed down by financial and healthcare stocks, as investors turn skittish following President-elect Donald Trump's remarks on the dollar and drug pricing.

Shortly before 6.30pm the Dow Jones had dropped 0.15% to 19,840, and the Nasdaq was 0.51% lower at 5,546.

Hong Kong stocks rose in earlier trade after yesterday's sell-off but traders were nervously awaiting a key Brexit speech by Prime Minister Theresa May as well as Donald Trump's inauguration later in the week. The Hang Seng Index added 123 points (0.54%) to close at 22,841, while Tokyo's Nikkei index lost 282 points (1.5%) to close at 18,814.