C&C Group has said it plans to cut 144 jobs across its Irish operations.
124 roles will be lost at its plant in Borrisoleigh, Co Tipperary, with a further 20 job losses at C&C depots in Portlaoise and New Ross.
The company is consolidating production at its manufacturing site in Clonmel, where it is investing €10m and creating 80 new jobs.
In addition, 10 new roles are to be created at its depot in Kilkenny, resulting in a net loss of 54 jobs in Ireland.
A further 127 jobs will be lost at its Shepton Mallet plant in England.
In a statement, the company said that production and packaging will be transferred on a phased basis from the facilities in Shepton Mallet and Borrisoleigh to Clonmel.
It said that Clonmel will become the core manufacturing site for both Bulmers and Magners cider, Tipperary Water and its range of premium beers and ciders.
The company said trading in the UK and Ireland has been intensely competitive over recent years, which resulted in significant downward pricing pressure and the loss of material contracts for private label water.
C&C added that while production at its Borrisoleigh site will cease, it will remain as a key transport hub for the company and both logistics and warehousing operations will be maintained in the town.
Around 15 employees will remain at the Borrisoleigh site to carry out these duties.
"This has been a difficult decision for the group and it is sad that the consolidation of production at the Clonmel site is the only viable option to maintain long term competitiveness," today's statement said.
It added that C&C recognises the impact on employees and will work to provide support, training, and where possible, alternative employment.