Trade between Ireland and the UK is likely to be worth in excess of €48.5bn, a bumper year for business between the islands.
Issues like the UK's position in Europe, the corporate tax rate and currency differentials could potentially have an impact in trade relations.
Steve Aiken, CEO of the British Irish Chamber of Commerce, said the relationship that these islands have with Europe as a whole was important and that the best position for Britain was remaining within the EU and linking with the EU single market.
Mr Aiken did not agree that Britain was joining in on the attack on Ireland's corporate tax rate.
"This is Britain trying to be as competitive as Ireland. It looks across and sees the success we've had here. One of the things that Britain is trying to do is make itself more competitive," he said. "Everything that works towards improving business on these islands is a good thing."
Steve Aiken said the currency differential can have an impact on trade, but he said the relationship is long term and the currency fluctuation is something they take into account.
"For some things like energy and food costs, that is something we have to monitor closely and see how it impacts on competitiveness," he added.
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