CRANN, a dedicated nanoscience research centre at Trinity College, is to create 50 full time research jobs.
The jobs are being created through an investment of €8m for nanoscience research this year, an increase of 60% over investment in 2011.
The centre said that €20m of industry funding for research has been committed over the next six years to sustain and strengthen the institute.
CRANN is funded by the Department of Jobs, Enterprise and Innovation through Science Foundation Ireland.
Ireland has been ranked as sixth in the world for its research in nanoscience and eighth for materials science research. CRANN researchers were responsible for 70% of the outputs leading to this national ranking.
Nanoscience supports 250,000 jobs in Ireland across the ICT, energy, medical and pharmaceutical sectors and accounts for 10% - €15 billion - of annual exports.
''A key part of the Government's plans for jobs and growth is ensuring not only that we continue to develop good ideas through scientific research, but also crucially that we turn more of them into products, services and ultimately good jobs,'' said the Minister for Jobs, Enterprise and Innovation Richard Burton.
''That is why we have put in place a series of changes to get more out of the state's investment in this area, including a research prioritisation exercise, a one-stop shop for commercialising research and a new highly ambitious strategy from SFI which aims to become the best science funding agency in the world,'' he added.