1,545 jobs are set to be created by five different companies across Ireland over the next five years, including 800 healthcare jobs.
The new roles will be in the healthcare, environmental services, software development and cloud technology sectors.
Irish private intellectual disability care service providers Nua Healthcare is to create 800 jobs over the next three years through the planned development of new residential and day care facilities.
300 of the positions are to be delivered this year across across social care, nursing and administrative support staff.
Nua has opened a new facility at Glenview House in Kilmallock, Co Limerick. The six-bed facility, which will be staffed by up to 30 social care professionals, will provide 24-hour care to adults with special needs with complex support requirements.
Glenview House is the first of seven facilities to open in the greater Munster region and marks the expansion of Nua outside of Leinster.
Minister of State at the Department of Health, Kathleen Lynch attended the official opening of the group's newest facility at Glenview House in Kilmallock, Co Limerick.
The growth plans will see a further 20 residential centres and associated day facilities being developed, increasing Nua's residential care capacity up to 280 individuals by 2019.
The care provider currently employs over 800 social care professionals and provides 160 residential and respite beds in 28 locations nationally - including Kildare, Laois, Wicklow, Offaly, Westmeath, Dublin, Tipperary, Limerick and Cork.
Meanwhile, French environmental services group Veolia is creating 300 jobs across its Irish operation over the next five years.
Veolia supplies water, waste and energy management services to both public and private organisations, including Irish Water.
The new roles would be across all of its divisions, including water infrastructure and biomass energy, which are the main growth areas at present for the firm.
The company employs 500 staff across Ireland and recently won a €450m contract to operate the country’s largest independent biomass power plant in Co Mayo, which opens in 2017.
First Data, a US company which is described as "a global leader in commerce-enabling technology and solutions", is to create 300 jobs in Nenagh, Co Tipperary.
The company is planning to open a Research and Development centre in the Co Tipperary town in early 2017.
Minister Alan Kelly described the announcement as the most significant day for the town in 30 years.
In a separate announcement, 100 new jobs are to be created by an Irish company that builds software to help airlines and travel companies gather and analyse large volumes of data, and extract value from it.
In particular Boxever, which employs 60 people, is looking for data scientists and software engineers to fill the roles.
The company's expansion comes after the firm secured $12m in fresh investment, bringing the total amount of money it has raised to $22m.
This latest investment follows a 463% growth in revenue at the company since the last round of funding closed in December 2013.
The firm has also added a range of new customers over the past 12 months, including airlines such as Emirates and Aer Lingus.
Among those putting money into the company are current investors Polaris Partners, Frontline Ventures and others, with Silicon Valley Bank contributing debt funding.
According to Boxever, it will use the fresh funding to expand its sales and customer support operations around the world, and increase its product and engineering teams.
Founded in 2011 by Dave O’Flanagan, Dermot O’Connor and Alan Giles, Boxever is headquartered in Dublin.
It also has an office in Boston.
Its cloud-based software uses big data and predictive analytics to figure out what is likely to elicit a response from customers, so that marketing and offers can be appropriately targeted at them.
Elsewhere, a Swedish provider of cloud-based services for online surveys in Europe, Netigate, is to create 45 new roles through the establishment of its international headquarters in Cork.
The jobs will be across sales, technical support and account management.
The announcement is supported by the Department of Jobs, Enterprise and Innovation.
Netigate has 1,500 customers in more than 30 countries, including Electrolux, Ericsson, The AA Ireland, BMW Group, and Spotify.