A pharmaceutical manufacturing company is to create 50 jobs in Dublin.
BioMarin Manufacturing Ireland, a subsidiary of BioMarin Pharmaceutical Inc, is to add the positions at its Dublin Global Commercial Operations Hub.
The expansion follows the announcement earlier this week that the European Commission had approved VIMIZIM, an enzyme replacement drug made by BioMarin.
The jobs will be in accounting, finance, customer service and marketing.
The Dublin operation has responsibility for international supply chain, logistics and high-level commercial decision making, including price, distribution and third party contracts for the launch of VIMIZIM.
BioMarin also has a biopharma manufacturing facility in Shanbally in Co Cork, which is expected to grow to 140 employees by 2015.
The investment is supported by the Department of Jobs, Enterprise and Innovation through IDA Ireland.
Minister for Jobs, Enterprise and Innovation Richard Bruton said the announcement was a further boost for the sector and for the city.
BioMarin Vice-President James Lennertz described Ireland as an ideal business environment and said Dublin was an essential part of the company's strategy.
Tesco opens latest store in Glenageary
Elsewhere, supermarket chain Tesco has opened its latest store at Park Pointe in Glenageary in Dublin.
The store will employ 65 people, with 45 coming from the Live Register.
Tesco said this latest recruitment will bring the total number of jobs the company will create this year to 250.
The retailer employs 15,000 people nationally and 2,300 in south Dublin.