Coronation Street actor William Roache has been found not guilty by a jury at Preston Crown Court of two counts of rape and four counts of indecent assault.
The 81-year-old, who plays Ken Barlow in the ITV soap, was said to have used his fame and popularity to exploit the "starstruck" girls, aged 16 and under, between the mid-60s and early 70s.
The jury spent five hours and 59 minutes deliberating before coming into court to deliver the verdicts at 11.19am.
Mr Roache was asked to stand and the jury foreman confirmed they were all agreed on verdicts on all of the counts.
Mr Roache made no reaction as he was cleared of all charges.
The women told jurors they were sexually abused by the defendant either at Granada Studios in Manchester, in his car or at properties he owned.
But Mr Roache told the jury he had no knowledge of any of the women and the alleged abuse simply did not happen.
Mr Roache said he was "astounded" and "horrified" at his arrest on suspicion of rape at his home in Wilmslow, Cheshire, on 1 May last year.
ITV announced he would not appear in the programme until legal proceedings were concluded.
The widespread publicity of the arrest led to four other women coming forward to allege they too had been victims in the same era.
Mr Roache was arrested again last June and then charged with five counts of indecent assault.
But the world's longest-serving soap actor, who has appeared in Coronation Street since its 1960 launch, told the jury sexual abuse was not in his "nature" and he had no interest in underage girls.
Louise Blackwell QC, defending, said the case against her client was "nonsense", with the trial haunted by the "spectre" of Jimmy Savile.
Criticism of police and prosecutors over Savile's impunity despite years of suspicions of sex abuse meant accusations against other celebrities had to end in a trial, it was suggested.
"In the post Jimmy Savile era, once someone makes an allegation, it's got to go to court, no sense will prevail, it has to go to court," Ms Blackwell said.
Glowing testimonies about Mr Roache's "caring" and "lovely" nature were given in evidence by three of his Coronation Street co-stars including Anne Kirkbride, who plays his on-screen wife Deirdre.
It was not credible, the jury were told, that the "perfect gentleman" and "father figure" they described had been a "sexual predator".
And the "inconsistencies and contradictions" of each complainant's "story" was picked apart under cross-examination.
During the trial, the prosecution offered no evidence on one of two counts of indecent assault, relating to one complainant, as she had "no actual memory of the episode".
The involvement of the press was also highlighted.
The husband of one complainant, whose sister was also allegedly abused, contacted the papers before the police, which "coloured" their allegations, Ms Blackwell said.
After Mr Roache's initial arrest for rape was "all over the press", she asked the jury whether any of the other women who came forward later could be regarded as "truly independent".
The trial lasted for four weeks.
Speaking to the media after the verdict, Mr Roache said there were "no winners" in these situations.
He thanked the jury and those who supported him, including ITV Granada, his management, legal team, family, friends and colleagues.
He added: "I think we should all be much kinder to ourselves. So now if you will excuse me, I'd like to get back to work."