At least 15 people have been killed and 47 have been injured in a suicide car bomb in central Damascus.
The bomb exploded near the Sabaa Bahrat Square, one of the capital's biggest roundabouts where the Syrian Central Bank is located.
The blast was followed by a massive cloud of smoke that rose from the residential and commercial area.
Elsewhere, United Nations Secretary-General Ban Ki-moon said all serious claims regarding the use of chemical weapons in Syria should be examined.
Mr Ban was speaking after meeting the head of the global chemical weapons monitoring body in The Hague today.
Mr Ban and Ahmet Uzumcu, head of the Organisation for the Prohibition of Chemical Weapons (OPCW), discussed details of a mission.
The mission is to investigate alleged chemical weapons use in Syria.
The scope of the mission has become a source of tension between Russia and Western powers seeking to broaden the probe.
They were due to address how and when a team of up to 15 inspectors can gain access to Syria.
Both rebels and government forces have accused each other of using chemical munitions.
Meanwhile, Goal CEO Barry Andrews has called on the international community to live up to its word and honour a commitment to help Syrian refugees.
Around €576m in emergency funds was pledged by the UN at the start of the year, but only 30% of the money has been delivered.
Over 70,000 people have died since violence broke out in the country two years ago.
Tens of thousands of displaced people are living in camps within Syria, tens of thousands more are living in refugee camps.
Mr Andrews said the funds are urgently needed to distribute emergency aid.