Fianna Fáil leader Micheál Martin has called for the resignation of Minister for Health James Reilly.
The move follows a report in today's Irish Times, which claims two locations in the minister's Dublin North constituency were added to a list of places chosen for primary care centres the night before the Government announced the plans.
Mr Martin said he believed there was an absence of leadership and a lack of direction at the Department of Health.
He said Mr Reilly "should step aside" as his "position had become untenable".
Róisín Shortall, who resigned as a junior minister in Health in the row over the selection process last September, said three months after Mr Reilly's decision to add locations to the list, the newly published documents showed there was no justification for it.
Speaking on RTÉ Radio, Ms Shortall again accused him of political interference and engaging in stroke politics.
She said there had been many convoluted excuses and justifications that Mr Reilly and other ministers gave in the Dáil and elsewhere where they tried to claim that there were other criteria used - that he had some basis other than pure political patronage.
She said his explanation that his decision was a logistical logarithmic progression was "absolute codswallop".