Property developer John McCabe has been ordered to repay more than €100m to NAMA arising mainly from loans to companies in his building group.
Mr Justice Peter Kelly also granted summary judgment orders in sums for about €31m against Mary McCabe, €36m against her son John, €29m each against her daughters Angela, Pauline and Sandra, and €18.3m against her daughter Helen McCarthy.
NAMA's actions against the McCabes arose from a series of loans advanced by the former Anglo Irish Bank, Bank of Ireland and AIB, all of which had been transferred to NAMA.
The agency brought the proceedings in the Commercial Court against the McCabes arising from its concerns over events that led to it obtaining court orders last month freezing the assets of Mr McCabe, Rath Stud, Ashbourne, Co Meath, and his family.
NAMA sought those orders after raising fears some €6.2m of assets that should have been ring-fenced to pay off debts was "misappropriated or dissipated" without consent of the agency.
The McCabes, whose group of companies owes NAMA more than €235m, had denied any wrongdoing.
The judge entered summary judgment in the sums sought and also granted European Enforcement Orders, meaning the judgments can be enforced across Europe.
Bernard Dunleavy, for the McCabes, said that while they were not contesting the judgment order applications, they regretted the breakdown of relations with NAMA and did not accept the allegations of bad faith.