A report from the National Suicide Research Foundation has said that frequently reported factors in suicides are significant loss of relationships, bereavement and finances.
It has found an association between the impact of the recession and suicide.
This is the first report of its kind from the foundation.
It examined 190 consecutive suicides in Cork city and county between September 2008 and March 2011.
The report points to a link between suicide and the impact of the recession and said there is a need to prioritise suicide prevention programmes during the recession.
Of those who died by suicide, 38% were unemployed and over 32% had been working in construction.
Over 68% of those who died had experienced past suicidal behaviour by family members or friends.
In the year prior to death, over 80% of people who died by suicide had been in contact with their GP or a mental health service.
The researchers also identified a cluster of 19 suicides involving adolescent and young adult men in a small area in Cork.
The project was funded by the HSE's National Office for Suicide Prevention.
Anyone concerned about issues surrounding suicide can contact Samaritans Ireland on 1850-60-90-90 or Aware on 1890-30-33-02.
Meanwhile, figures also show that over 9,800 people attended hospital emergency departments last year due to deliberate self-harm, a 4% reduction on the previous year's figure.