The Abbott healthcare company is seeking 29 voluntary redundancies from its staff at its Finisklin plant in Sligo.
There are currently over 400 people employed in the diagnostics facility.
The company says there is over-capacity in the manufacturing area.
It is seeking the voluntary redundancies in both the manufacturing area and support roles.
It says it is offering a competitive package and outplacement services including assistance with training.
Abbott employs almost 4,000 people in 13 sites in eight counties, but says the announcement regarding the Finisklin plant in Sligo does not impact on any of its other sites.