US medical devices firm Stryker is to cut 142 jobs at its facility in Co Cork.
The announcement was made to staff at a series of meetings held at the two plants in Carrigtwohill.
In a statement, the manufacturer of orthopaedic implants and instruments, said the company's two manufacturing facilities at Carrigtwohill are to be consolidated into a single facility over the next four years.
The manufacturing of certain products made there will be transferred to Stryker facilities outside of Ireland.
However, the company added that they expect to create approximately 60 new jobs over the next four years in the development of the company's endoscopy division
It hopes that some of the current staff will re-skill and transfer to these new posts.
Stryker has three manufacturing facilities in Ireland, two employing at total of 700 people at Carrigtwohill in Co Cork, and one in Limerick employing 500 people.
Earlier this year, Stryker acquired Boston Scientific's neurovascular division, including its Cork operation, bringing its total employment in Ireland to 2,000 people.