The company already employs 1,300 people in Ireland.
In addition to management consultancy, Accenture provides technology services and outsourcing. It has more than 200,000 employees in 120 countries.
The jobs will be based at a new research and innovation centre and will involve advanced statistical modelling for companies and governments.
Accenture has six other such centres around the world and the company's clients include 75% of the Fortune 500 global companies.
It is recruiting staff with analytical and statistics experience from graduate to PhD level.
The company moved its corporate base from Bermuda to Ireland last year.
This is the first significant jobs announcement since the world's focus switched to Ireland's debt crisis.
The new jobs come despite some calls for Ireland's 12.5% corporation tax rate to be reviewed as part of the EU/IMF bailout programme.
