India said it has contained an outbreak of bird flu in the remote north-eastern state of Manipur after slaughtering nearly 300,000 birds.

However, state authorities were monitoring the health of four children with fever who had handled dead or sick fowl, and have sent their blood and throat swab samples for testing.

The flare-up of the H5N1 virus in chickens in a small poultry farm near Manipur's capital, Imphal, was the country's first in a year, prompting authorities to kill all poultry and destroy eggs within a 5km radius.

Manipur borders Myanmar, which reported two outbreaks of bird flu in chickens in July alone.

Officials said they were also investigating the deaths of about 120 chickens in Mizoram state, which neighbours Manipur.

India had two major outbreaks last year in its western region -- both of which were successfully contained.

Avian influenza of the H5N1 strain has killed at least 192 people out of 319 cases, and led to millions of chickens and ducks being slaughtered in dozens of nations.