It will be Scherzinger's first foray into fashion design and her collection will feature a 30-piece mixture of dresses, jumpsuits, skirts and tops.
The X Factor judge said of the collaboration, "I'm so excited to be collaborating with Missguided! I've worn their clothes in the past as I'm a big fan. This is my first time designing my own collection and I can't imagine a more perfect fit."
Missguided's Managing Director, Nitin Passi, added, "Working with Nicole was a natural choice for us. She's personable, fun and loves to experiment with fashion, all qualities that truly represent our customer. She is a great ambassador for the brand and we're excited to see the response to the collection."
The Nicole x Missguided collection will launch in March and will be available from misguided.co.uk.