The actress will star alongside Guy Pearce and Hugo Weaving in the Australian independent thriller, which will be directed by Kim Farrant and produced by Dragonfly Pictures (Australia) and Fastnet Films (Ireland).
The film centres on parents Catherine and Matthew Parker, whose relationship is pushed to the brink when their two teenage children disappear into the remote Australian desert.
The film is being co-financed by Worldview Entertainment, the Irish Film Board and Screen Australia who have said the project has "a strong creative vision and massive A-list festival potential".
With a script by Fiona Seres and Irish screenwriter Michael Kinirons will go into production in early 2014.
Kidman can next be seen in the 2014 biopic Grace of Monaco.