Brendan Gleeson is to star opposite Kate Beckinsale, Michael Caine, Ben Kingsley, Jim Sturgess and David Thewlis in the thriller Eliza Graves.

Deadline.com, which broke the news of Gleeson and Thewlis' casting, says Eliza Graves is based on the Edgar Allan Poe short story The System of Doctor Tarr and Professor Fether and is directed by Brad Anderson (Fringe, The Machinist).

It tells the story of a young doctor who comes to work at a psychiatric institution and falls in love with a beautiful patient.

Production is due to begin next week.