Former Holby City and Emmerdale star Patsy Kensit will be among Brendan O'Connor's guests on The Saturday Night Show on RTÉ One at 10:05pm.
Kensit, we are told, will explain to O'Connor why "she's an Irish mammy at heart".
The founder of the Jack & Jill Foundation, Jonathan Irwin, will recount his own tragic-yet-inspiring story.
Also joining O'Connor will be the artist Guggi and author Helen Seymour.
Music on the night will be of the country variety from siblings Mary, Kathleen and Davey Keenan.