Grey's Anatomy fans have been told to expect plenty of new castings in the ninth season.

In a Q&A session with fans, TV Guide's Natalie Abrams was asked about the new series.

She replied: "Among the new castings for the season premiere — besides two new docs, a couple of medical professionals and a new resident — are two flight attendants.

"Either [creator] Shonda Rhimes really wants to make the fans suffer with a flashback to the actual crash, or the Stranded Six Five will have to get back on the horse plane to return to Seattle. Where's Dr Perkins [James Tupper] when you need him?"

The ninth season of Grey's Anatomy begins in the US in September.